It was in Barrio Antioquia where Escobar first encountered smuggling routes, in this place he met Griselda Blanco, also known with as the "coca queen”, the drug trafficker with the longest running in the business and who he learned from the business.

Barrio Antioquia was a kind of office for Escobar and in one of the main outlets in the city of Medellin, it could be said that it was the main office of the "Patron" which is recognized by its inhabitants as a simple man who shared money and security, who kept the neighborhood organized and safe.